Revaccination With mRNA-1345 for RSV Maintains Robust Immunogenicity, Safety

Revaccination With mRNA-1345 for RSV Maintains Robust Immunogenicity, Safety

Revaccination with mRNA-1345 against RSV at 12 months was noninferior to primary vaccination among adults aged 50 years and older.

Revaccination with Moderna’s mRNA-1345 vaccine for respiratory syncytial virus (RSV) is well tolerated and demonstrates noninferior immunogenicity compared with the primary dose, according to study results published in Clinical Infectious Diseases.

Investigators conducted a phase 3, randomized, multicenter clinical trial to assess the safety, tolerability, and antibody response of a 50-µg dose of mRNA-1345 vaccine administered 12 months after a primary dose in adults aged 50 years and older.

According to study results published in Clinical Infectious Diseases.

Author's summary: mRNA-1345 revaccination shows promise.

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Infectious Disease Advisor Infectious Disease Advisor — 2025-10-27

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