What are possibilities for early diagnosis of head and neck squamous cell carcinoma?

Possibilities for Early Diagnosis of Head and Neck Squamous Cell Carcinoma

Head and neck squamous cell carcinoma (HNSCC) is a diverse group of cancers originating from the mucosal linings of the oral cavity, oropharynx, hypopharynx, and larynx.

Globally, HNSCC is the sixth most common type of cancer, presenting significant health challenges due to its late-stage diagnosis, which often leads to poor prognosis and reduced quality of life.

Principal risk factors for HNSCC include chronic consumption of alcohol and tobacco, with additional factors such as betel nut chewing contributing significantly in certain regions like Central and South Asia.

Despite advancements in treatment modalities, the late detection of HNSCC remains a critical issue, highlighting the urgent need for effective early diagnosis and screening methods.

Early diagnosis involves both "screening" asymptomatic individuals and "case detection" in patients with identified lesions.

This review comprehensively examines the current methodologies and updates in early diagnosis practices for HNSCC.

Author's summary: Early diagnosis of HNSCC is crucial for improving prognosis.

Medical Dialogues — 2025-10-27

Possibilities for Early Diagnosis of Head and Neck Squamous Cell Carcinoma

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